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. 2022 Dec 5;12:20967. doi: 10.1038/s41598-022-25594-4

Table 3.

Socio-demographic and contextual factors associated with current e-cigarette use among youth by multi-level regression analyses.

Univariate analyses Multi-level model 1 Multi-level model 2
Crude OR (95% CI) Adj. OR (95% CI) Adj. OR (95% CI)
Age groups (in years)
11–13 1  < 0.001 1  < 0.001 1  < 0.001
14 1.3 (1.1, 1.4) 1.2 (1.2, 1.3) 1.2 (1.2, 1.3)
15 1.3 (1.1, 1.5) 1.3 (1.2, 1.34) 1.3 (1.2, 1.3)
 ≥ 16 1.7 (1.49, 2.0.) 1.3 (1.3, 1.4) 1.3 (1.2, 1.4)
Sex
Female 1 1  < 0.001 1  < 0.001
Male 3.2 (2.9, 3.6)  < 0.001 1.7 (1.6, 1.7) 1.7 (1.6, 1.7)
Current cigarette smoker
No 1 1  < 0.001 1  < 0.001
Yes 12.4 (11.2, 13.7)  < 0.001 9.9 (9.6,10.4) 9.9 (9.5, 10.3)
Contextual factors
E-cigarette regulatory policy status
NRP 1 1
LRP 2.5 (2.0, 3.1)  < 0.001 0.9 (0.8, 1.1) 0.401
RP 2.2 (1.8, 2.5)  < 0.001 1.8 (1.6, 2.0)  < 0.001
MRP 0.8 (0.6, 1.0) 0.069 0.6 (0.6, 0.7)  < 0.001
World Bank taxonomy
lMIC 1 1
uMIC 1.6 (1.3, 1.8)  < 0.001 1.1 (1.0, 1.2) 0.011
HIC 2.8 (2.4, 3.2)  < 0.001 2.4 (2.2, 2.7)  < 0.001
Random-effects parameters
School level SD 0.00000003 0.00000002
SE 0.000664 0.0004885
Country level SD 0.8746556 0.6879336
SE 0.208748 0.0182421
Model comparison
Likelihood Chi-square statistic 4384.7 2552.8
Ratio testa P value 0.0000 0.0000

aBased on the results on likelihood ratio tests, estimates of multilevel logistic regression were preferred than fixed effect models.

SD-standard deviation, SE-standard error.

*Ages 11–13 and ≥ 16 were merged owing to small numbers.