HGG |
High Grade Glioma |
GBM |
Glioblastoma Multiforme |
CNS |
Central Nervous System |
MRI |
Magnetic Resonance Imaging |
EGFR |
Epidermal Growth Factor Receptor |
PTEN |
Phosphatase and Tensin homolog Gene |
IDH |
Isocitrate Dehydrogenase |
TCA |
Tricarboxylic Acid Cycle |
BRAF |
Serine/ Threonine-protein kinase B-Raf |
PDGFR |
Platelet-Derived Growth Factor Receptor |
BBB |
Blood Brain Barrier |
TME |
Tumor Microenvironment |
CTLs |
Cytotoxic T Lymphocytes; |
WT1 |
Wilms Tumor protein 1 |
CMV |
Cytomegalovirus |
pp65 |
Phosphoprotein 65 |
EphA2 |
Ephrin type-A receptor 2 |
IL13Ra2 |
Interleukin-13 Alpha 2 |
DCV |
Dendritic Cell Vaccines |
MAGE-1 |
Melanoma-Associated Antigen-1 |
AIM-2 |
Antigen isolated from Immunoselected Melanoma-2 |
TRP-2 |
Tyrosine-Related Protein-2 |
gp100 |
Glycoprotein 100 |
HSV-1 |
Herpes Simplex type 1 Virus |
DIPG |
Diffuse Intrinsic Pontine Glioma |
ICB |
Immune Checkpoint Blockade |
CTLA-4 |
Cytotoxic T Lymphocyte-associated Antigen 4 |
PD-1 |
Programmed cell Death protein 1 |
PD-L1 |
Programmed cell Death protein ligand 1 |
MSI |
Microsatellite Instability |
ADC |
Antibody and antibody Drug Conjugates |
NK |
Natural Killer cells |
mAbs |
Monoclonal Antibodies |
ADCC |
Antibody Dependent Cell mediated Cytotoxicity |
CAR |
Chimeric Antigen Receptor; |
DMG |
Diffuse Midline Gliomas |
C7R |
Interleukin-7 Receptor; |
KIRs |
Killer Inhibitory Receptors |
CRS |
Cytokine Release Syndrome |
ICANS |
Immune effector Cell-Associated Neurotoxicity Syndrome |
MDSCs |
Myeloid-Derived Suppressor Cells |
iNOS |
Inducible Nitric Oxide Synthase |
TK |
Thymidine Kinase |
Flt3L |
Fms-like Tyrosine Kinase Ligand; |
IDO |
Indoleamine 2 3 Dioxygenase |
Arg1 |
Arginase |
HIF-1a |
Hypoxia-Inducible Factor-1 Alpha |
PGE2 |
Prostaglandin E2; |
TAMs |
Tumor-Associated Macrophages/Microglia |
DAB |
3,3’-Diaminobenzidine. |