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. 2022 Jul 20;29(60):89954–89968. doi: 10.1007/s11356-022-21932-1

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© The Author(s) 2022

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Fig. 4 — Photomicrograph of H&E-stained sections of the rat inner ear. CCM+GEN-treated groups (A–D). CCM+NaS-treated groups (E–H). Organ of Corti (Oc) with decreased hair cells, spiral ganglia (Sg), and Reissener’s membrane (Rm) (A). The higher magnification of the circle of A represent organ of Corti (B). The higher magnification to the spiral ganglion (Sg) of A showed a few hypereosinophilic neurons (arrowhead), congested blood vessels (zigzag arrows), and some vacuoles (arrows) (C). Stria vascularis with three layers of cells, marginal cells (M), intermediate cells (I), and basal cells (B), showed mild congestion in the vessels (arrow), also the spiral ligament (SL) with mild vacuolation (arrowhead) (D). Organ of Corti and spiral ganglion of NaS+CCM-treated groups (E). Higher magnification to the organ of Corti with its hair cells (HC) and spiral ganglion in F and G. The stria vascularis and the spiral ligament (SL) appeared normal (H)