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. 2022 Jul 20;29(60):89954–89968. doi: 10.1007/s11356-022-21932-1

Table 1.

Effect of CCM treatment on the distribution of DPOAE amplitudes for 1–8-kHz frequencies in the ear of GEN or NaS administered rats

Frequencies Control OO CCM GEN NaS CCM+GEN CCM+NaS
1 kHz 15.03 ± 0.57 15.95 ± 0.97 17.50 ± 1.51 10.72* ± 1.33 12.33* ± 0.26 13.05 ± 0.27 13.93 ± 0.93
2 kHz 16.37 ± 0.58 16.85 ± 0.70 17.17 ± 1.06 10.72* ± 0.65 12.60* ± 0.17 13.43*# ± 0.26 13.55* ± 0.41
3 kHz 14.65 ± 0.66 13.95 ± 0.22 15.83 ± 1.10 11.72* ± 0.48 12.77* ± 0.11 14.23# ± 0.32 14.10 ± 0.35
4 kHz 14.72 ± 0.88 14.53 ± 0.29 15.50 ± 0.81 11.82* ± 0.55 12.42* ± 0.27 14.83# ± 0.54 15.33# ± 0.81
5 kHz 16.92 ± 0.64 16.85 ± 0.65 18.33 ± 0.36 11.53* ± 0.47 12.33* ± 0.37 13.87*# ± 0.76 14.20*# ± 0.65
6 kHz 15.53 ± 0.40 15.47 ± 1.71 16.83 ± 1.12 11.10* ± 0.31 12.12* ± 0.48 14.32# ± 0.61 14.82# ± 0.59
7 kHz 17.82 ± 1.01 16.57 ± 2.38 17.83 ± 0.70 10.58* ± 0.52 11.62* ± 0.21 15.35# ± 0.54 16.07# ± 1.30
8 kHz 17.77 ± 0.63 18.42 ± 1.99 20.00 ± 1.35 11.33* ± 0.42 12.23* ± 0.33 16.67# ± 0.64 18.93# ± 1.10

Values are represented as the mean ± SE. n = 10 replicates/treatment

OO olive oil

*Significantly different compared to the control group (i.e., CCM, GEN, NaS, GEN+CCM, or CCM+NaS vs. control group) at P < 0.05

#Significantly different from the respective drug only treated group (i.e., CCM+GEN vs. GEN and CCM+NaS vs. NaS) compared to the control group at P < 0.05