Table 4.

The hazard ratios for mortality according to tertiles of B-type natriuretic peptide in patients without left ventricular hypertrophy on electrocardiography.

	Unadjusted HR (95% CI)	Model 1a (95% CI)	Model 2b (95% CI)	Model 3c (95% CI)	Model 4d (95% CI)
Patients without LVH
Tertile 1*	REF	REF	REF	REF	REF
Tertile 2†	4.66 (3.48–6.25)	2.83 (2.09–3.83)	2.85 (2.13–3.91)	2.80 (2.05–3.83)	2.86 (2.08–3.93)
Tertile 3‡	9.86 (7.45–13.07)	5.14 (3.82–6.91)	5.27 (3.91–7.10)	4.74 (3.46–6.48)	4.72 (3.42–6.53)

HR, hazard ratio; CI, confidence interval; LVH, left ventricular hypertrophy; REF, reference.

*The range of BNP levels in tertile 1 is ≤ 37 pg/mL.

^†The range of BNP levels in tertile 2 was between > 37 and < 167 pg/mL.

^‡The range of BNP levels in tertile 3 is ≥ 167 pg/mL.

^aModel 1: Adjusted for age and sex.

^bModel 2: Adjusted for age, sex, systolic blood pressure, and diastolic blood pressure.

^cModel 3: Adjusted for age, sex, systolic blood pressure, diastolic blood pressure, and comorbidities (hypertension, diabetes mellitus, ischemic stroke, hemorrhagic stroke, heart failure, coronary artery disease, chronic kidney disease, and end-stage renal disease).

^dModel 4: Adjusted for age, sex, systolic blood pressure, diastolic blood pressure, comorbidities (hypertension, diabetes mellitus, ischemic stroke, hemorrhagic stroke, heart failure, coronary artery disease, chronic kidney disease, and end-stage renal disease), and components of hypertension-mediated organ damage (estimated glomerular filtration rate, cardiomegaly on chest radiography, and myocardial ischemia on electrocardiography).