Table 4.

Association between area deprivation index and incident dementia in cognitively unimpaired at baseline participants.

	Incident Dementia* (outcome)
ADI ranking, per decile	Model 1			Model 2			Model 3
	HR‡	95% CI	p-value	HR‡	95% CI	p-value	HR‡	95% CI	p-value
State ADI ranking	1.06	(1.01, 1.11)	0.010	1.06	(1.01, 1.11)	0.012	1.06	(1.01, 1.11)	0.015
National ADI ranking	1.09	(1.02, 1.16)	0.008	1.08	(1.02, 1.15)	0.010	1.08	(1.02, 1.15)	0.013

Abbreviations: HR, hazards ratio; CI, confidence interval.

^*All dementia cases, including those ascertained by medical record review.

^‡HR (95% CI) retained from Cox proportional hazards models with age as the time scale; model 1 is unadjusted (events/total: 293/3911; mean(SD) follow-up for events/non-events: 6.0(2.6)/5.9(3.2)); model 2 is adjusted for years of education (events/total: 293/3910; mean(SD) follow-up for events/non-events: 6.0(2.6)/5.9(3.2)); model 3 is additionally adjusted for sex, and Apolipoprotein E ε4 allele status (events total: 292/3786; mean(SD) follow-up for events/non-events: 6.0(2.6)/6.0(3.1)).