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. 2022 Nov 4;38(12):1569–1587. doi: 10.1007/s12264-022-00959-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A new rehabilitation strategy that integrates multiple technologies and integrates sensorimotor information to achieve ipsilateral motor control. In patients with unilateral CNS injury, sensory information from the paralyzed limb is increased by using sensors, electrical stimulation, and surgery, and specific sensory information is decoded. The decoded information is then directly transmitted to specific regions of the contralesional hemisphere by electrical stimulation. At the same time, the motor commands from the contralesional cortex are extracted, and the motor information is decoded according to the data set during training, and then the exoskeleton is directly controlled to drive the affected limb and complete the corresponding action.