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. 2022 Sep 2;19(6):1752–1771. doi: 10.1007/s13311-022-01277-w

Table 2.

Manchester criteria for diagnosis of NF2, diagnosis of Nf2 requires to meet primary and added features as mentioned below

Primary finding Added features needed for diagnosis
Bilateral Vestibular Schwannoma None
First-degree relative with NF2 Unilateral Vestibular Schwannoma, or Any two (2) other NF2-Associated lesions: Meningioma, Schwannoma, Ependymoma, or Juvenile Cataracts
Unilateral Vestibular Schwannoma Any two (2) other NF2-Associated lesions: Meningioma, Schwannoma, Ependymoma, or Juvenile Cataract
Multiple Meningiomas Unilateral Vestibular Schwannoma, or Any two (2) other NF2-Associated lesions:Schwannoma, Ependymoma, or Juvenile Cataracts