Table 1.
Viral vectors commonly used for neural circuit research.
| Type | Virus (abbreviation) |
Family, genus | Genomic type | ||
|---|---|---|---|---|---|
| Non-transsynaptic (static) | Adeno-associated virus (AAV) | Parvoviridae, Dependovirus | Single-stranded DNA | ||
| Lentivirus (LV) |
Retroviridae, Lentivirus |
Single-stranded RNA | |||
| Canine adenovirus (CAV) | Adenoviridae, Mastadenovirus | Double-stranded DNA | |||
| Semliki Forest virus (SFV) | Togaviridae, Alphavirus | Single-stranded RNA | |||
| Rabies virus with the envelope glycoprotein gene deleted (RV-ΔG) |
Rhabdoviridae, Lyssavirus |
Negative-sense single-stranded RNA | |||
| Herpes simplex virus amplicon (HSV amplicon) |
Herpesviridae, α herpesvirinae |
Double-stranded DNA | |||
| Transsynaptic | Trans-multisynaptic | Anterograde, multisynaptic | Herpes simplex virus (HSV) H129 |
Herpesviridae, α herpesvirinae |
Double-stranded DNA |
| Vesicular stomatitis virus (VSV) |
Rhabdoviridae, Vesiculovirus |
Negative-sense single-stranded RNA | |||
| Sindbis virus (SINV) |
Togaviridae, Alphavirus |
Single-stranded RNA | |||
| Retrograde, multisynaptic | Pseudorabies virus, PRV Bartha |
Herpesviridae, α herpesvirinae |
Double-stranded DNA | ||
| Wild-type Rabies virus (WT RV) |
Rhabdoviridae, Lyssavirus |
Negative-sense single-stranded RNA | |||
| Trans-monosynaptic | Anterograde, monosynaptic | Herpes simplex virus with TK-deleted (HSV-ΔTK) |
Herpesviridae, α herpesvirinae |
Double-stranded DNA | |
| Adeno-associated virus, serotype 1 (AAV-1) |
Parvoviridae, Dependovirus |
Single-stranded DNA | |||
| Retrograde, monosynaptic | RVΔG-EnvA |
Rhabdoviridae, Lyssavirus |
Negative-sense single-stranded RNA | ||
| Pseudorabies virus with TK-deleted (PRV-ΔTK) |
Herpesviridae, α herpesvirinae |
Double-stranded DNA | |||