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. 2022 Nov 16;54(11):1991–2006. doi: 10.1038/s12276-022-00875-0

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Lnc Tmem235 competes with BIRC5 mRNA to bind miR-34a-3p, thereby releasing the silencing effect of miR-34a-3p on BIRC5 mRNA and promoting the expression of BIRC5 protein; this inhibits hypoxia-induced apoptosis of BMSCs in the femoral head necrotic area to ultimately improve the osteogenic repair effect of BMSCs on early SONFH.