Table 3.
The associations between phthalates and NAFLD in US adults.
| Phthalate | NAFLD | Ln CAP | ||
|---|---|---|---|---|
| metabolites | (CAP ≥274 dB/m) | |||
| OR (95%CI) | P FDR | β (95%CI) | P FDR | |
| MECPP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 2.277 (1.277, 4.06) | 0.016 | 0.044 (0.008, 0.079) | 0.027 |
| Q3 | 1.435 (0.663, 3.107) | 0.335 | 0.007 (−0.043, 0.057) | 0.777 |
| Q4 | 2.719 (1.296, 5.700) | 0.016 | 0.067 (0.017, 0.118) | 0.027 |
| MEOHP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 1.662 (0.999, 2.764) | 0.068 | 0.021 (−0.025, 0.067) | 0.510 |
| Q3 | 1.452 (0.967, 2.179) | 0.068 | 0.006 (−0.049, 0.060) | 0.826 |
| Q4 | 2.016 (1.102, 3.687) | 0.068 | 0.036 (−0.005, 0.076) | 0.243 |
| MEHHP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 2.110 (1.009, 4.409) | 0.047 | 0.020 (−0.049, 0.089) | 0.552 |
| Q3 | 1.816 (1.106, 2.981) | 0.037 | 0.051 (0.008, 0.094) | 0.072 |
| Q4 | 2.073 (1.111, 3.867) | 0.037 | 0.046 (−0.002, 0.094) | 0.085 |
| MCiNP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 1.662 (1.013, 2.728) | 0.134 | 0.034 (−0.025, 0.093) | 0.415 |
| Q3 | 1.558 (0.788, 3.081) | 0.185 | 0.024 (−0.040, 0.089) | 0.433 |
| Q4 | 1.618 (0.917, 2.854) | 0.136 | 0.031 (−0.027, 0.089) | 0.415 |
| MCiOP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 0.976 (0.567, 1.678) | 0.925 | −0.027 (−0.078, 0.023) | 0.403 |
| Q3 | 2.409 (1.028, 5.643) | 0.108 | 0.070 (0.011, 0.130) | 0.072 |
| Q4 | 1.645 (0.950, 2.847) | 0.108 | 0.022 (−0.033, 0.077) | 0.408 |
| MOiNP | ||||
| Q1 | Ref. | Ref. | ||
| Q2 | 1.266 (0.485, 3.299) | 0.607 | 0.003 (−0.053, 0.058) | 0.923 |
| Q3 | 1.901 (0.871, 4.146) | 0.298 | 0.045 (−0.002, 0.092) | 0.177 |
| Q4 | 1.556 (0.643, 3.766) | 0.454 | 0.022 (−0.025, 0.069) | 0.499 |
Data are expressed as odds ratio (95% Confidence interval [CI]) or β (95% Confidence interval [CI]). Odds ratios (95% CIs) were adjusted for age, gender, race.
BMI, total cholesterol level, systolic blood pressure, educational level, smoking status, diabetes status and physical activity.
NHANES, National Health and Nutrition Examination Survey. All P-values were corrected by FDR (the same in Table 4).