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Sirt1 and Nrf2 inhibition abolished the anti-inflammation and anti-apoptosis effects of ciprofol in vitro. The mRNA levels of IL-6 (A), IL-17A (B) and TNF-α (C) were measured (n = 6). (D) Representative images of TUNEL staining in each group (n = 5). ∗p < 0.05 compared to the PBS group. # p < 0.05 compared to the ISO group. & p < 0.05 compared to the ISO + ciprofol group.
