Table 1.
Characteristics of patients with pediatric acute respiratory distress syndrome.
| Characteristics | Mild PARDS (n = 33) | Moderate PARDS (n = 44) | Severe PARDS (n = 44) | Total (n = 121) | p-Value |
|---|---|---|---|---|---|
| Age, years | 4.5 (0.8, 12.6) | 3.3 (0.6, 9.4) | 1.5 (0.5, 5.1) | 2.8 (0.6, 9.4) | 0.227 |
| Male gender | 19 (57.6) | 25 (56.8) | 31 (70.5) | 75 (62.0) | 0.348 |
| Weight, kg | 13.9 (8.6, 32.3) | 12.6 (6.7, 30.2) | 9.7 (6.2, 14.3) | 12 (6.9, 29.2) | 0.183 |
| BMI, kg/m2 | 16.5 (13.6, 20.0) | 16.8 (13.7, 19.1) | 16.9 (15.2, 19.2) | 16.7 (13.8, 19.3) | 0.996 |
| Comorbidity | 0.328 | ||||
| Neuromuscular | 6 (19.4) | 14 (37.8) | 9 (23.1) | 29 (27.1) | |
| Respiratory | 2 (6.5) | 2 (5.4) | 4 (10.3) | 8 (7.5) | |
| Heme-oncology | 2 (6.5) | 3 (8.1) | 5 (12.8) | 10 (9.4) | |
| Genetic/congenital | 5 (16.1) | 10 (27.0) | 6 (15.4) | 21 (19.6) | |
| Neoplastic | 2 (6.5) | 1 (2.7) | 4 (10.3) | 7 (6.5) | |
| Others | 3 (9.7) | 4 (10.8) | 3 (7.7) | 10 (9.4) | |
| PIM 2 | 5.5 (2.8, 22.2) | 6.2 (3.2, 15.8) | 11.3 (4.4, 24.3) | 7.1 (3.3, 20.9) | 0.269 |
| PELOD | 9 (1, 11) | 2 (1, 14) | 10 (1.5, 20) | 10 (1, 13.5) | 0.489 |
| Risk factor | |||||
| Pneumonia | 21 (63.6) | 26 (59.1) | 31 (70.5) | 78 (64.5) | 0.422 |
| Aspiration | 3 (9.1) | 7 (15.9) | 4 (9.1) | 14 (11.6) | |
| Sepsis | 4 (12.1) | 9 (20.5) | 7 (15.9) | 20 (16.5) | |
| Others | 5 (15.2) | 2 (4.6) | 2 (4.6) | 9 (7.4) | |
| Bacteremia | 2 (6.1) | 6 (13.6) | 7 (15.9) | 15 (12.4) | 0.410 |
| Respiratory pathogen | |||||
| Bacterial | 10 (30.3) | 14 (31.8) | 21 (47.2) | 45 (37.2) | 0.192 |
| Viral | 15 (45.5) | 22 (50.0) | 24 (54.6) | 61 (50.4) | 0.730 |
| Fungal | 2 (6.1) | 3 (6.8) | 9 (20.5) | 14 (11.6) | 0.069 |
| None | 8 (24.2) | 8 (18.2) | 9 (20.5) | 25 (20.7) | 0.809 |
| Air leak | 1 (3.0) | 2 (4.6) | 5 (11.4) | 8 (6.6) | 0.273 |
| Multiorgan dysfunction | 18 (56.3) | 27 (61.4) | 36 (81.8) | 81 (67.5) | 0.035 |
| POPC admission | 1.5 (1, 4) | 3 (1, 4) | 2 (1, 4) | 2 (1, 4) | 0.297 |
| POPC discharge | 4 (1, 4) | 4 (4, 4) | 4 (4, 4) | 4 (3, 4) | 0.253 |
| PCPC admission | 1.5 (1, 4) | 3 (2, 4) | 2 (1, 4) | 2 (1, 4) | 0.166 |
| PCPC discharge | 3 (1, 4) | 4 (3, 4) | 4 (3,4) | 4 (3,4) | 0.046 |
Continuous and categorical variables summarized in medians (interquartile ranges) and counts (percentages), respectively.
BMI, body mass index; PIM 2, Pediatric Index of Mortality 2; PELOD, pediatric logistic organ dysfunction; PARDS, pediatric acute respiratory distress syndrome; POPC, pediatric overall performance category; PCPC, pediatric cerebral performance category.