Table 1.

Changes in global splicing in new suppressor alleles

Events\Allele	prp-8(R540K)	prp-8(D1549N)	snrp-200(N18K)
Alt 3′ss		30	1
Alt 5′ss	1	73	19
Skipped exon		3
Retained intron		10	5
Multi-skip exon		1
Mut. Excl. exon
Alt first exon		4	1
Alt last exon

For each suppressor allele, we identify the number of events of each type with changes in splicing relative to an unsuppressed strain as determined by mRNASeq analysis. The number of events that fit the criteria of having a minimum of 15 junction spanning reads in each library, a ΔPSI > 0.15 for all nine pairwise comparisons (pairSum = 9), and a mean ΔPSI > 0.20 for the nine pairwise comparisons are indicated.