TABLE 1.

Kinetic parameters for the AncC wild type and Gln45Met mutant

	AncC13			AncC Gln45Met
	K M (mM)	k cat (s −1)	K i (mM)	K M (mM)	k cat (s −1)	K i (mM)
HMP	7 ± 2	0.40 ± 0.06	31 ± 17	6 ± 1	0.28 ± 0.03	68 ± 21
PL	28 ± 9	0.20 ± 0.04	85 ± 54	1.3 ± 0.4	0.008 ± 0.001	N/A
ATP‐Mg a	1 ± 0.2	0.080 ± 0.005	44 ± 19	1.3 ± 0.2	0.22 ± 0.01	N/A

Note: Mean ± SEM are shown.

Abbreviation: N/A, not applicable.

^a10 mM of HMP was used as co‐substrate.