Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 2;10(12):e005543. doi: 10.1136/jitc-2022-005543

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Bulk RNA-seq to evaluate immune landscape in 4T1-hPD-L1 tumors. Tumor-bearing mice received six doses of antibodies. Then, tumor tissues were collected for bulk RNA-seq assay. (A) The heat map showing differentially expressed gene profiles. (B) The levels of Ifng, Tnf, Gzma, and Gzmb. (C–H) The heat maps representing the expression levels of genes belonging to immune signatures. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 mean the significant difference compared with BiTP-treated samples. TGF-β, transforming growth factor-beta.