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. 2022 Nov 21;24(11):e37683. doi: 10.2196/37683

Table 1.

Summary of commonly reported outcomes by disease in which the outcome was investigated.

Disease and motor function outcome category Motor function outcome
Acquired brain injury

Gross motor impairment or performance and upper body
  • Peak upper limb velocity [35]

  • Upper limb velocity [35]

Alzheimer disease

Fine motor impairment or performance and continuous motion
  • Spiral tracing [82]

Depressive tendencies

Fine motor impairment or performance and discrete motion
  • Finger tap speed [92]

  • Flight time [92]

  • Hold time [92]

Healthy participants

Bradykinesia
  • Bradykinesia score [94,100]


Dyskinesia
  • Dyskinesia score [100]


Fine motor impairment or performance and continuous motion
  • Spiral tracing [82,90]


Fine motor impairment or performance and discrete motion
  • Correct finger taps [25,83]

  • Finger tap accuracy [38,101]

  • Finger tap count [38,95,101]

  • Finger tap duration [38,101]

  • Finger tap interval [38,101]

  • Finger tap reaction time [38,42,58]

  • Finger tap rhythm [42,95]

  • Finger tapping test [102]

  • Flight time [83,88,103]

  • Hold time [88]


Gait

Gross motor impairment or performance and lower body
  • Lower limb velocity [105]


Gross motor impairment or performance and whole body
  • Joint velocity [106]


Motor symptom severity
  • Rest tremor [102]


Postural stability
  • Trunk acceleration [50]

Huntington disease

Cognitive impairment
  • Stroop Color and Word Test [96]


Dyskinesia

Fine motor impairment or performance, discrete motion
  • Finger tap speed [96]


Gait
  • Step cadence [99]

Mild cognitive impairment

Fine motor impairment or performance and continuous motion
  • Spiral tracing [82]

Multiple sclerosis

Fine motor impairment or performance and discrete motion
  • Finger tap count [25]


Gait
  • Turning speed [26]

Neurological disordersa

Fine motor impairment or performance and continuous motion
  • Spiral tracing [90]

Neuromuscular disordersb

Gait
  • Step count [104]

Parkinson disease

Bradykinesia

Cognitive impairment
  • Stroop Color and Word Test [83]


Dyskinesia
  • Dyskinesia score [53,100]

  • Finger tapping test [56]


Fine motor impairment or performance and discrete motion
  • Correct finger taps [83,109]

  • Finger tap accuracy [38,101]

  • Finger tap count [38,95,101]

  • Finger tap duration [38,101]

  • Finger tap interval [38,101]

  • Finger tap reaction time [38,42,49]

  • Finger tap rhythm [42,95]

  • Finger tapping test [102]

  • Flight time [88,103,110]

  • Hold time [88]


Gait

Gross motor impairment or performance and upper body
  • Peak upper limb velocity [33]


Gross motor impairment or performance and whole body
  • Joint velocity [106]


Motor fluctuations

Motor symptom severity

Postural stability
  • Trunk acceleration [50]

Rapid eye movement (REM) sleep behavior disorder

Fine motor impairment or performance and discrete motion
  • Finger tap reaction time [42]

  • Finger tap rhythm [42]

Stroke

Gait
  • Step cadence [81]

  • Step count [41,74]

  • Step length [81]

  • Walking speed [41,81]

Transthyretin familial amyloid polyneuropathy

Gait
  • Lower limb velocity [78]

  • Step length [78]

  • Stride duration [78]

  • Walking speed [78]


Gross motor impairment or performance and upper body
  • Upper limb velocity [78]

aIncluding Parkinson disease, Huntington disease, early dementia, cerebral palsy, and poststroke.

bIncluding Duchenne muscular dystrophy, limb-girdle muscular dystrophy, and spinal muscular atrophy.