Table 4.
Adverse Events Reported in The Literature for Patients with Advanced Cancer and Hepatitis B Infection Treated with ICI
| Any grade | Grade1 | Grade2 | Grade3-4 | |
|---|---|---|---|---|
| Treatment-related Aes | ||||
| Diarrhoea | 1 | 0 | 0 | 1 |
| Rash | 2 | 1 | 1 | 0 |
| Fatigue | 2 | 1 | 1 | 0 |
| Hypothyroidism | 1 | 0 | 1 | 0 |
| Pneumonitis | 3 | 0 | 2 | 1 |
| Vitiligo | 1 | 1 | 0 | 0 |
| Colitis | 1 | 0 | 0 | 1 |
| Laboratory-treatment related Aes | ||||
| ALT elevation | 122 | 49 | 37 | 36 |
| AST elevation | 63 | 44 | 1 | 18 |
| Hyperglycemia | 4 | 0 | 1 | 3 |
| Thrombocytopenia | 2 | 1 | 0 | 1 |
| Neutropenia | 1 | 0 | 0 | 1 |
| Unspecified Aes | 27 | 0 | 0 | 27 |
ALT=Alanine transaminase; AST=Aspartate aminotransferase