Table 3.
The association between absolute LAE change patterns and MCI reversion in eight activities.
| Rarely-rarely | Rarely-occasionally | Rarely-frequently | Occasionally -rarely | Occasionally-occasionally | Occasionally -frequently | Frequently-rarely | Frequently-occasionally | Frequently-frequently | |
|---|---|---|---|---|---|---|---|---|---|
| Cognitive activity | |||||||||
| Read newspapers/books | |||||||||
| No of reverters/ person years | 1,436/11,693 | 46/212 | 74/322 | 37/258 | 8/24 | 15/61 | 41/340 | 12/46 | 49/193 |
| Reversion rate | 46.9 | 71.9 | 77.1 | 51.4 | 100.0 | 83.3 | 44.1 | 80.0 | 83.1 |
| HR (95%CI) | 1 ref | 1.53 (1.10–2.13) * | 1.49 (1.12–1.98) ** | 1.04 (0.71–1.52) | 1.84 (0.87–3.91) | 1.74 (0.89–3.43) | 0.88 (0.61–1.26) | 1.69 (0.87–3.29) | 1.62 (1.16–2.27) ** |
| Watch TV and/or listen to radio | |||||||||
| No of reverters/ person years | 2,078/2,706 | 53/358 | 232/1,335 | 60/817 | 39/203 | 138/730 | 180/2,615 | 83/630 | 728/3,767 |
| Reversion rate | 29.1 | 54.1 | 62.4 | 30.2 | 65.0 | 71.5 | 28.3 | 49.7 | 69.0 |
| HR (95%CI) | 1 ref | 1.74 (1.22–2.46) ** | 1.93 (1.54–2.42) *** | 0.93 (0.66–1.31) | 2.31 (1.57–3.41) *** | 1.87 (1.44–2.43) *** | 0.81 (0.64–1.03) | 1.59 (1.18–2.16) ** | 1.93 (1.58–2.35) *** |
| Physical activity | |||||||||
| Housework | |||||||||
| No of reverters/ person years | 308/3,840 | 31/226 | 164/752 | 59/735 | 9/54 | 54/205 | 258/3,329 | 42/333 | 796/3,689 |
| Reversion rate | 29.8 | 46.3 | 73.5 | 30.4 | 52.9 | 87.1 | 32.7 | 50.6 | 77.7 |
| HR (95%CI) | 1 ref | 1.67 (1.12–2.50) * | 2.31 (1.85–2.89) *** | 0.96 (0.70–1.32) | 2.04 (0.96–4.35) | 2.79 (2.03–3.84) *** | 0.92 (0.74–1.13) | 1.54 (1.05–2.26) * | 2.23 (1.84–2.70) *** |
| Personal outdoor activities | |||||||||
| No of reverters/ person years | 185/2,181 | 43/268 | 265/1,264 | 61/707 | 31/149 | 106/503 | 255/2,813 | 91/563 | 567/2,877 |
| Reversion rate | 30.8 | 53.8 | 72.4 | 32.2 | 72.1 | 74.6 | 34.9 | 58.7 | 68.1 |
| HR (95%CI) | 1 ref | 1.65 (1.12–2.43) * | 1.86 (1.49–2.32) *** | 1.02 (0.73–1.41) | 2.02 (1.34–3.05) ** | 1.73 (1.30–2.31) *** | 0.92 (0.73–1.16) | 1.42 (1.06–1.91) * | 1.76 (1.43–2.16) *** |
| Garden work | |||||||||
| No of reverters/ person years | 1,285/10,771 | 46/216 | 152/647 | 66/456 | 3/11 | 8/24 | 94/750 | 14/57 | 50/221 |
| Reversion rate | 26.2 | 30.6 | 29.5 | 26.5 | 36.4 | 33.3 | 26.3 | 29.8 | 29.4 |
| HR (95%CI) | 1 ref | 1.45 (1.04–2.01) * | 1.39 (1.31–1.70) ** | 1.10 (0.83–1.47) | 1.80 (0.25–12.85) | 2.21 (0.98–4.96) | 0.87 (0.68–1.10) | 1.54 (0.87–2.73) | 1.38 (0.98–1.94) |
| Social activity | |||||||||
| Raise domestic animals | |||||||||
| No of reverters/ person years | 908/8,080 | 47/240 | 161/750 | 76/609 | 3/25 | 33/145 | 214/2,090 | 30/161 | 248/1,057 |
| Reversion rate | 42.0 | 71.2 | 71.9 | 48.7 | 37.5 | 78.6 | 44.0 | 71.4 | 81.3 |
| HR (95%CI) | 1 ref | 1.66 (1.20–2.29) ** | 1.72 (1.42–2.09) *** | 1.12 (0.86–1.48) | 1.04 (0.33–3.23) | 1.69 (1.13–2.54) * | 0.84 (0.71–1.01) | 1.18 (0.76–1.84) | 1.46 (1.22–1.74) *** |
| Play cards and/or mahjong | |||||||||
| No of reverters/ person years | 1,347/11,062 | 58/262 | 68/314 | 62/446 | 10/55 | 22/92 | 68/523 | 16/92 | 66/300 |
| Reversion rate | 46.1 | 74.4 | 80.1 | 48.8 | 66.7 | 81.5 | 51.9 | 66.7 | 81.5 |
| HR (95%CI) | 1 ref | 1.47 (1.09–1.99) * | 1.64 (1.21–2.23) ** | 1.02 (0.75–1.38) | 1.20 (0.59–2.42) | 1.26 (0.79–1.99) | 1.03 (0.79–1.35) | 0.91 (0.51–1.62) | 1.48 (1.10–1.98) ** |
| Social activities (organized) | |||||||||
| No of reverters/ person years | 1,353/11,123 | 144/667 | 58/254 | 82/606 | 17/71 | 9/52 | 35/293 | 14/53 | 5/16 |
| Reversion rate | 46.1 | 77.4 | 85.3 | 49.7 | 89.5 | 75.0 | 43.4 | 93.3 | 100.0 |
| HR (95%CI) | 1 ref | 1.41 (1.15–1.73) ** | 2.07 (1.50–2.84) *** | 1.03 (0.79–1.34) | 1.46 (0.82–2.59) | 1.30 (0.61–2.76) | 0.89 (0.60–1.32) | 1.62 (0.83–3.15) | 1.70 (0.70–4.14) |
*
P < 0.05
**
P < 0.01
***
P < 0.001.
Adjusted for age (continuous), gender, residence, years of schooling, marital status, economic status, living pattern, number of people living with, tobacco smoking, alcohol drinking, regular exercise, ADL, IADL, chronic disease (hypertension, diabetes, heart disease, stroke or CVD, cataract, digestive system disease, arthritis, Parkinson's disease).