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Reagents and conditions: (i) NaN3, Bu4NHSO4, satd. NaHCO3/CHCl3 (1:1), rt, 20 min; (ii) 30% aq. NH3, MeOH, rt, 3 days; (iii) 4,4′-dimethoxytrityl chloride (DMTCl), pyridine, 0°C to rt, overnight; (iv) long-chain aminoalkyl CPG (LCAA-CPG-CO2H), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC), Et3N, 4-(dimethylamino)pyridine (DMAP), pyridine/DMF (1:1), rt, 3 days.
