Table 1. Reaction Optimization^a.

^aStandard reaction conditions: 1 (0.20 mmol), p-TolI (20 mol %), Selectfluor (0.30 mmol), Py·HF (4–16 mmol), Et₃N (0.22–1.50 mmol), DCE (0.50 mL), 24 h, room temperature.

^bYield and dr determined by ¹⁹F NMR with α,α,α-trifluorotoluene as an internal standard.

^cp-TolI was excluded from the reaction mixture.

^d0.50 mmol scale.

^eIsolated yield.

^fHeated to 50 °C.