TABLE 4.
Risk Factors for Persistent Symptoms
| Univariable | Multivariablea | |||
|---|---|---|---|---|
| Relative Risk | P | Relative Risk | P | |
| Sex (male vs female) | 0.93 (0.82, 1.06) | 0.28 | 0.95 (0.80, 1.13) | 0.55 |
| Age | 1.00 (1.00, 1.00) | 0.42 | 1.00 (1.00, 1.00) | 0.44 |
| History of prematurity | 1.01 (0.87, 1.18) | 0.88 | 1.07 (0.89, 1.29) | 0.48 |
| Exclusive breastfeeding | 1.05 (0.92, 1.19 | 0.51 | 1.07 (0.87, 1.32) | 0.53 |
| Acid suppression | 1.18 (1.05, 1.33) | 0.007 | 1.10 (0.94, 1.28) | 0.24 |
| Hypoallergenic formula | 1.18 (1.04, 1.33) | 0.007 | 1.17 (0.98, 1.39) | 0.07 |
| Thickening | 0.96 (0.80, 1.14) | 0.62 | 0.77 (0.60, 0.97) | 0.03 |
| Aspiration status | ||||
| Known to aspirate | 0.86 (0.77, 0.96) | 0.01 | 0.89 (0.69, 1.16) | 0.39 |
| Known to not aspirate | 1.00 | 1.00 | ||
| Status unknown | 0.76 (0.67, 0.86) | <0.001 | 0.75 (0.58, 0.97) | 0.03 |
a
Adjusted for acid suppression, hypoallergenic formula, thickening, aspiration status, age at hospital admission, history of prematurity, sex, breastfeeding status.