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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: NMR Biomed. 2022 Mar 21;36(6):e4715. doi: 10.1002/nbm.4715

TABLE 1.

List of select diaCEST probes along with their exchange properties

diaCEST contrast agent Concentration B0, B1, tsat Chemical shifts (ppm) T, pH Exchange rate (s−1) References
Porphyrin (TPPS4) 20 mM 9.4 T, 3.6 μT, 3 s −9.75 37 °C, 6.6 430 51
D-glucose 20 mM 9.4 T, 1.6 μT, 4 s 1.2 37 °C, 6.8 4280 189
Glutamate 20 mM 9.4 T, 3.6 μT, 5 s 3 37 °C, 7 5000 190
Creatine 25 mM 11.7 T, 6 μT, 3 s 1.9 37 °C, 6.5 ~175 47
Iopamidol 20 mM 4.7 T, 2.5 μT, 5 s 4.3, 5.5 37 °C, 6.5 265 71
I45DC-diGlu 25 mM 11.7 T, 5.9 μT, 3 s 4.5, 7.8 37 °C, 7.5 5300 88
Salicylic acid 25 mM 11.7 T, 7.2 μT, 3 s 9.3 37 °C, 7 1200 56
Olsa 10 mM 11.7 T, 3.6 μT, 3 s 9.8 37 °C, 7.4 697 157