TABLE 1.
Effects of LPS administration in vivo on cell counts and differential countsa
| Time after LPS injection (h) | No.
(109/liter) of:
|
% of CD3+ CD4+ lymphocytes | ||
|---|---|---|---|---|
| Leukocytes | Lymphocytes
|
|||
| Total | CD3+ CD4+ | |||
| 0 | 5.00 ± 0.50 | 1.67 ± 0.12 | 0.79 ± 0.09 | 46.40 ± 2.80 |
| 3 | 3.99 ± 0.57* | 0.36 ± 0.03* | 0.14 ± 0.03* | 36.29 ± 4.79* |
| 6 | 10.77 ± 0.91* | 0.28 ± 0.02* | 0.07 ± 0.02* | 23.73 ± 3.31* |
| 24 | 11.73 ± 0.46* | 1.62 ± 0.11 | 0.77 ± 0.07 | 47.67 ± 3.36 |
a
Values are means ± SE for seven health subjects. LPS (4 ng/kg) was given as an intravenous bolus injection at 0 h. Analysis was performed by flow cytometry and FACScan analysis. *, P < 0.05 in comparison with the baseline, as determined by the Wilcoxon test.