Table 3.

Pericyte sources for tissue models.

Organ	in vivo or primary cell LAM Expression	Cell Source	Evaluated in vitro LAM Expression
“Generic” PC	• N/A	hiPSC: Orlova et al., 2014; Wanjare et al., 2014; Kumar et al., 2017; Reviewed in Xu et al., 2017 and Browne et al., 2021	• Upregulates VCAM-1 (191)
Brain PC	• Baseline VCAM-1 • Upregulates ICAM-1, VCAM-1 • No selectin expression	Primary Human	• Baseline VCAM-1 • Upregulates ICAM-1, VCAM-1 • No selectin expression
		hiPSC: Faal et al., 2019; Stebbins et al., 2019	• Did not evaluate
Lung PC	• Upregulates ICAM-1, VCAM-1	Primary Human	• Upregulates ICAM-1, VCAM-1
		Immortalized Human	• Upregulates ICAM-1, VCAM-1
Kidney PC (Mesangial Cells)	• Upregulates ICAM-1 • No selectin expression	Primary Human	• Upregulates ICAM-1 • No selectin expression
Liver PC (Hepatic Stellate Cells, Ito)	• Baseline ICAM-1, VCAM-1 • Upregulates ICAM-1, VCAM-1	Primary Human	• Baseline ICAM-1, VCAM-1 • Upregulates ICAM-1, VCAM-1

N/A, not applicable; PC, pericyte; LAM, leukocyte adhesion molecule; VCAM-1, vascular cell adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1; hiPSC, human induced pluripotent stem cell.