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. 2022 Nov 7;19(14):1995–2007. doi: 10.7150/ijms.69626

Figure 5.

Figure 5

The role of SK4 channels in the activity of atrial fibroblasts from canines. (A) Immunofluorescence staining of SK4 (green) and α-SMA (red) in atrial fibroblasts in the Ang II-treated groups (400×). (B) Immunofluorescence staining of α-SMA (red) in atrial fibroblasts in the Ad-GFP (green)-treated groups (400×). (C) The values of SK4 AOD in the Ang II-treated groups. ***P<0.001 versus the control group. ##P<0.01 versus the Ang II group. ▲▲P<0.01 versus the control group. (D) The values of α-SMA AOD in all the groups of atrial fibroblasts. AOD= IOD/area. (E-I) Representative Western blot images and mean levels of SK4, α-SMA, collagen I and collagen III in all the groups of atrial fibroblasts. ***P<0.001; ##P<0.01; ###P<0.001; ▲▲P<0.01; ▲▲▲P<0.001. The data are presented as the mean ± SD, n=6.