. 2000 Mar;68(3):1019–1025. doi: 10.1128/iai.68.3.1019-1025.2000

TABLE 1.

Number of mice with diffuse hypercellularity

Strain	Phenotype	Time (day p.i.) when penicillin treatment was started^b	No. of animals with diffuse hypercellularity at following percentile^a:
Strain	Phenotype	Time (day p.i.) when penicillin treatment was started^b	60th	70th	80th
NZAN0	Ska1⁻ Em^r Kan^r	7	6/15	3/15	1/15
NZAN5	Ska1⁻ Em^r Kan^r Skc5⁺	7	6/25	2/25	0/25
NZAN0	Ska1⁻ Em^r Kan^r	16	2/14	2/14	0/14
NZAN5	Ska1⁻ Em^r Kan^r Skc5⁺	16	5/16	2/16	0/16
NZAN1	Ska1⁻ Em^r Kan^r Ska1⁺	16	18/36^***	9/36^***	2/36
Uninfected mice
NZAN0 and NZAN5 controls^c			7/23	3/23	0/23
NZAN1 controls^d			0/10	0/10	0/10

Corresponds to a value below which the designated percentage of the total calculated glomeruli of the uninfected control group is found. We defined diffuse hypercellularity when more than 50% of the glomeruli analyzed in a mouse displayed cell numbers above that of the percentile of the uninfected control mice in the same experiment. Data are given as the number with diffuse hypercellularity/total number tested. ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.001 (degree of significance for the occurrence of diffuse hypercellularity, compared to the uninfected controls in the same experiment).

All animals were sacrificed on day 21 p.i.

Uninfected mice belonging to the same experiment as NZAN0- and NZAN5-infected mice.

Uninfected mice belonging to the same experiment as NZAN1-infected mice.