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. 2022 Dec 2;28:e938298-1–e938298-16. doi: 10.12659/MSM.938298

Table 4.

Summary of clinical studies on post-stroke patients using tFUS.

Study No. Targeted lesion Study design Intervention Frequency Intensity Location Schedule Follow-up Outcome
Zhou et al, 2017 [198] 80 (40) Acute cerebral infarction RCT tFUS and acupoint application vs conventional 800 KHz 0.75 w/cm2 Temporal window on the lesion side 30 d N/A Neurological function deficiency scale positive
Wang et al, 2020 [199] 45 (15) Stroke RCT tFUS vs motor imagery vs conventional 800 KHz 1.2 W/cm2 Temporal window on the lesion side 20 min for 4 weeks N/A FMA, MBI positive
Pu et al, 2021 [200] 114 (38) Stroke with upper limb disorder RCT tFUS vs motor imagery vs conventional 800 KHz 1.2 W/cm2 Temporal window on the lesion side 20 min for 4 weeks N/A FMA, MBI positive

FMA – Fugl-Meyer Assessment; MBI –Modified Barthel Index.