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. Author manuscript; available in PMC: 2022 Dec 6.
Published in final edited form as: Neuromuscul Disord. 2019 Nov 19;30(1):38–46. doi: 10.1016/j.nmd.2019.11.005

Fig. 5.

Fig. 5.

Structural analysis of DNAJB6 mutations. (A) Protein homology model showing predicted location of residues A50, E54, S57, and F91. The region coded for by exon 5 (G/F domain) is shown in blue and the J domain in orange. A50 and E54 are located close to F91 in the interface between the J- and G/F-domains, whereas S57 is not in this area. (B) Protein sequence alignment of selected vertebrate DNAJB6 orthologs, showing conservation of the A50 and E54 residues. For the full alignment, see online supplementary file 1.