Table 1.
A summary of GWAS summary statistics for six different serum biomarkers.
| Exposures | Dataset source | Sample size | NSNP | R2(%) | F |
|---|---|---|---|---|---|
| Cystatin C | UK Biobank | 361194 | 234 | 9.59 | 163.6084 |
| Total bilirubin | UK Biobank | 361194 | 99 | 28.21 | 1433.199 |
| Urate | UK Biobank | 361194 | 188 | 7.35 | 152.2644 |
| Creatinine | UK Biobank | 361194 | 243 | 4.15 | 64.37972 |
| Kidney injury molecule 1 levels | SCALLOP | 21,758 | 11 | 13.68 | 313.1804 |
| Growth differentiation factor-15 levels | SCALLOP | 21,758 | 18 | 5.67 | 72.59881 |
NSNP, the number of SNP included in the MR analysis; R2(%), the proportion of variance explained by included SNPs of each exposure; F, the general F statistic for each biomarker.