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Bacterial replication in spleens and lungs from C57BL/6, C3H, and BALB/c mice vaccinated with empty V1Jns.tPA vector (control) or plasmid DNA encoding the 22-kDa antigen and challenged intravenously with 106 M. tuberculosis H37Rv 8 weeks after the third DNA injection (data expressed as mean ± SD of log10 values of number of CFU per spleen or lungs; four to six mice per group).
