Figure EV3. DCA suppresses production of IL‐17A in Th17 and Tc17 cells.

• A, B
  CD4⁺ (A) and CD8⁺ (B) T cells were isolated from spleens and LNs of WT mice. Purified T cells were polarized under Th17‐inducing conditions and treated with increasing concentrations of DCA for 3 days. Representative contour plots show the frequencies of IL‐17A⁺ and IFN‐γ⁺ cells analyzed by flow cytometry (n = 3 biological replicates; n.s., not significant; *P = 0.01–0.05; **P = 0.001–0.01; data are analyzed by the two‐tailed unpaired Student's t‐test).