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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: J Comp Neurol. 2022 Jun 30;530(16):2835–2851. doi: 10.1002/cne.25379

FIGURE 2.

FIGURE 2

Brain-wide mapping of melanocortin-3 receptor (MC3R) neurons. Three-dimensional rendering of an MC3R-Cre::tdTomato brain viewed in the sagittal plane (a). Scale bar, 500 μm. Coronal view of MC3R labeling in the same brain at the level of the prelimbic and insular cortex (b), arcuate nucleus, ventromedial hypothalamus and basomedial, central and medial amygdala (c), and subiculum and periaqueductal gray (d). Scale bars, 500 μm. MC3R cell density in the whole brain was quantified by registering cell locations to the Allen Common Coordinate Reference Framework (e and f)