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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: J Comp Neurol. 2022 Jun 30;530(16):2835–2851. doi: 10.1002/cne.25379

FIGURE 5.

FIGURE 5

Melanocortin-3 receptor (MC3R) labeling is sexually dimorphic. Low magnification images (left, middle column) and comparison of the number of MC3R neurons (right column) in male and female MC3R-Cre::tdTomato mice (a–e). The number of MC3R neurons was significantly higher in the anteroventral periventricular nucleus hypothalamus (AVPV) (a), principal nucleus of the bed nucleus of the stria terminalis (BSTPr) (b), and ventral premammillary nucleus (PMv) (e) in females. In contrast, the number of MC3R neurons was significantly higher in males in the arcuate nucleus hypothalamus (ARH) (c), and no differences were found in the MeApd (d). Scale bar, 200 μm. Data were analyzed with Student’s unpaired t-test. *p < .05, **p < .01, ****p < .0001