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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: J Comp Neurol. 2022 Jun 30;530(16):2835–2851. doi: 10.1002/cne.25379

FIGURE 6.

FIGURE 6

Brain-wide mapping of melanocortin-3 receptor (MC3R) projections. Three-dimensional rendering of an MC3R-Cre::SynTom brain viewed in the sagittal plane. Scale bar, 500 μm. Coronal view of MC3R projections in the same brain at the level of the nucleus accumbens (b), arcuate nucleus, ventromedial hypothalamus and basomedial, central and medial amygdala (c), and brainstem (d). Scale bars, 500 μm. MC3R fiber density in the whole brain was quantified by registering the mean fluorescence intensity in each brain region to the Allen Common Coordinate Reference Framework (e and f)