Table 3.
Variable | No. of patients | % | |
---|---|---|---|
Gender | |||
Male | 25 | 71 | |
Female | 10 | 29 | |
Primary tumor | |||
Colon | 26 | 74 | |
Rectum | 9 | 26 | |
Dukes' stage | |||
B | 13 | 37 | |
C | 22 | 63 | |
Synchronous | |||
Yes | 15 | 43 | |
No | 20 | 57 | |
No. of pathological lesions | |||
1 | 12 | 34 | |
2–4 | 18 | 51 | |
>4 | 5 | 14 | |
DFI | |||
<12 months | 20 | 55 | |
≥12 months | 15 | 45 | |
Margins | |||
>1 cm | 18 | 51 | |
<1 cm | 17 | 48 | |
Positive margins (≤0.1 cm) | 4 | 11 | |
Previous chemotherapy | |||
Yes | 25 | 71 | |
No | 10 | 29 | |
Previous CPT-11, yes | 12 | 34 | |
Age, years | |||
Median | 58 | ||
Range | 41–75 | ||
Preoperative CEA | |||
>30 ng/ml | 4 | 11 | |
Postoperative CEA | |||
>5 ng/ml | 4 | 11 | |
Size of metastatic lesion | |||
≥5 cm | 7 | 20 | |
Metastatic lesions | |||
Bordering vessels, yes | 16 | 46 | |
≥2 vessels, yes | 2 | 6 | |
Central, yes | 4 | 11 | |
Bordering vena cava, yes | 2 | 6 | |
Bilobar | 14 | 40 | |
Above normal | |||
Preoperative CEA | 19 | 54 | |
Postoperative CEA | 4 | 11 | |
LDH | 0 | 0 | |
Alkaline phosphatase | 22 | 63 | |
Bilirubin | 5 | 14 | |
AST | 3 | 9 |
DFI, disease free interval; CEA, carcinoembryonic antigen; LDH, lactic dehydrogenase; AST, aspartate aminotransferase.