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. 2022 Nov 22;13:946740. doi: 10.3389/fendo.2022.946740

Table 4.

STROBE Statement—A checklist of items and the completeness of reporting score (COR %) for the included studies (n = 21).

Item No. Recommendation Criteria Met (N, %) Yes No N/A
Title and abstract 1 (a) Indicate the study’s design with a commonly used term in the title or the abstract 21(100) 0 (0) 0 (0)
(b) Provide in the abstract an informative and balanced summary of what was done and what was found 21 (100) 0 (0) 0 (0)
Introduction
Background/rationale 2 Explain the scientific background and rationale for the investigation being reported 21 (100) 0 (0) 0 (0)
Objectives 3 State-specific objectives, including any prespecified hypotheses 21 (100) 0 (0) 0 (0)
Methods
Study design 4 Present key elements of study design early in the paper 21 (100) 0 (0) 0 (0)
Setting 5 Describe the setting, locations, and relevant dates, including periods of recruitment, exposure, follow-up, and data collection 21 (100) 0 (0) 0 (0)
Participants 6 (a) Cohort study—Give the eligibility criteria, and the sources and methods of selection of participants. Describe methods of follow-up
Case–control study—Give the eligibility criteria, and the sources and methods of case ascertainment and control selection. Give the rationale for the choice of cases and controls
Cross-sectional study—Give the eligibility criteria, and the sources and methods of selection of participants
N/A
3 (100)
16 (76.1)
N/A
0 (0)
2 (9.6)
N/A
0 (0)
3 (14.3)
(b) Cohort study—For matched studies, give matching criteria and number of exposed and unexposed
Case–control study—For matched studies, give matching criteria and the number of controls per case
3 (100) 0 (0) 0 (0)
Variables 7 Clearly define all outcomes, exposures, predictors, potential confounders, and effect modifiers. Give diagnostic criteria, if applicable 19 (90.4) 2 (9.6) 0(0)
Data sources/measurement 8* For each variable of interest, give sources of data and details of methods of assessment (measurement). Describe comparability of assessment methods if there is more than one group 21 (100) 0 (0) 0 (0)
Bias 9 Describe any efforts to address potential sources of bias 19(90.4) 2 (9.6) 0 (0)
Study size 10 Explain how the study size was arrived at 20 (95.2) 1 (4.8) 0 (0)
Quantitative variables 11 Explain how quantitative variables were handled in the analyses. If applicable, describe which groupings were chosen and why 21 (100) 0 (0) 0 (0)
Statistical methods 12 (a) Describe all statistical methods, including those used to control for confounding 20 (95.2) 1 (4.8) 0 (0)
(b) Describe any methods used to examine subgroups and interactions 21 (100) 0 (0) 0 (0)
(c) Explain how missing data were addressed 3 (14.3) 2 (9.6) 16 (76.1)
(d) Cohort study—If applicable, explain how loss to follow-up was addressed
Case–control study—If applicable, explain how matching of cases and controls was addressed
Cross-sectional study—If applicable, describe analytical methods taking account of sampling strategy
20 (95.2) 1 (4.8) 0 (0)
( e ) Describe any sensitivity analyses 20 (95.2) 0 (0) 1 (4.8)
Results
Participants 13* (a) Report numbers of individuals at each stage of study—e.g., numbers potentially eligible, examined for eligibility, confirmed eligible, included in the study, completing follow-up, and analyzed 21 (100) 0 (0) 0 (0)
(b) Give reasons for non-participation at each stage 5 (23.8) 3 (14.3) 13 (61.9)
(c) Consider use of a flow diagram 0 (0) 21 (100) 0 (0)
Descriptive data 14* (a) Give characteristics of study participants (e.g., demographic, clinical, social) and information on exposures and potential confounders 19 (90.4) 1 (4.8) 1 (4.8)
(b) Indicate number of participants with missing data for each variable of interest 2 (9.6) 1 (4.8) 18 (85.6)
(c) Cohort study—Summarize follow-up time (e.g., average and total amount) N/A N/A N/A
Outcome data 15* Cohort study—Report numbers of outcome events or summary measures over time N/A N/A N/A
Case–control study—Report numbers in each exposure category, or summary measures of exposure 3(100) 0 (0) 18 (0)
Cross-sectional study—Report numbers of outcome events or summary measures 19 (90.4) 2 (9.6) 0 (0)
Main results 16 (a) Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (e.g., 95% confidence interval). Make clear which confounders were adjusted for and why they were included 19 (90.4) 2 (9.6) 0 (0)
(b) Report category boundaries when continuous variables were categorized 13 (61.9) 1 (4.8) 7 (33.3)
(c) If relevant, consider translating estimates of relative risk into absolute risk for a meaningful time period 13 (61.9) 5 (23.8) 3 (14.3)
Other analyses 17 Report other analyses done—e.g., analyses of subgroups and interactions, and sensitivity analyses 21 (100) 0 (0) 0 (0)
Discussion
Key results 18 Summarize key results with reference to study objectives 21 (100) 0 (0) 0 (0)
Limitations 19 Discuss limitations of the study, taking into account sources of potential bias or imprecision. Discuss both direction and magnitude of any potential bias 11 (52.4) 10 (47.6) 0 (0)
Interpretation 20 Give a cautious overall interpretation of results considering objectives, limitations, multiplicity of analyses, results from similar studies, and other relevant evidence 15 (71.4) 6 (28.6) 0 (0)
Generalisability 21 Discuss the generalizability (external validity) of the study results 9 (42.9) 12 (57.1) 0 (0)
Other information
Funding 22 Give the source of funding and the role of the funders for the present study and, if applicable, for the original study on which the present article is based 13 (61.9) 7 (33.3) 1 (4.8)
Completeness of Reporting mean of the 21 studies (%) 87.0 ± 6.4%

"*" refer to Vandenbroucke et al., (71).