| 1 |
Pregnancy |
| 2 |
Known intolerance to aspirin, clopidogrel, heparin, cobalt chromium, sirolimus, contrast material |
| 3 |
Known thrombocytopaenia (platelet count <100,000/mm3) |
| 4 |
Contraindications to PCI, stenting, ASA, clopidogrel, prasugrel or ticagrelor |
| 5 |
Cardiogenic shock |
| 6 |
Significant comorbidities precluding clinical follow-up (as judged by investigators) |
| 7 |
Major planned surgery that requires discontinuation of dual antiplatelet therapy |
| 8 |
History of stenting in the target bifurcation lesion |
| 9 |
Renal insufficiency (GFR/MDRD <45 ml/min), which in the operator’s opinion precludes contrast injection during repeat OFDI pullback |
| 10 |
Severely tortuous or angulated coronary anatomy of the study vessel that in the opinion of the investigator would result in suboptimal optical frequency domain imaging (OFDI) or excessive risk of complication to place an OFDI catheter |
| 11 |
Target lesion reference vessel diameter (RVD) <2.25 and >4 mm |
| 12 |
Target bifurcation lesion has a previously implanted stent |
| ASA: acetylsalicylic acid; GFR: glomerular filtration rate; MDRD: Modification of Diet in Renal Disease; PCI: percutaneous coronary intervention |
