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. 2022 Feb 18;17(15):1252–1259. doi: 10.4244/EIJ-D-21-00425

Table 4. Predictors of variability.

Univariate predictors of absolute difference >0.03 between 1st and 2nd QFR analysis Multivariate analysis
p-value OR p-value
FFR/0.10 0.002 0.73 (0.55-0.98) 0.036
Observer (1 as reference)
2 0.037 2.75 (1.13-6.71) 0.026
3 0.014 3.39 (1.38-8.33) 0.008
4 <0.001 9.08 (3.55-23.21) 0.000
5 <0.001 5.98 (2.41-14.8) 0.000
Contrast flow velocity (0.05-0.15 m/s as reference)
0.16-0.25 m/s 0.049 1.35 (0.72-2.56) 0.352
>0.25 m/s 0.245 0.85 (0.30-2.41) 0.760
Angiographic quality score/1 unit 0.003 0.72 (0.53-0.99) 0.041
FFR: fractional flow reserve; OR: odds ratio; QFR: quantitative flow ratio