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. 2021 Mar 19;16(16):1318–1325. doi: 10.4244/EIJ-D-19-00296

Table 3. Clinical outcomes by total stent length.

Variables Total stent length (mm) Unadjusted Multivariate adjusted Adjusted by inverse probability of treatment weights (IPTW)
≤40 (N=8,035) >40 (N=1,182) HR p-value HR p-value HR p-value
Target lesion failure 369 (4.6%) 102 (8.6%) 1.92 (1.54-2.39) <0.001 1.76 (1.40-2.21) <0.001 1.88 (1.67-2.13) <0.001
Death Cardiac death 207 (2.6%) 54 (4.6%) 1.81 (1.34-2.44) <0.001 1.61 (1.17-2.20) 0.003 1.43 (1.20-1.70) <0.001
Non-cardiac death 131 (1.6%) 33 (2.8%) 1.75 (1.19-2.56) 0.004 1.44 (0.95-2.17) 0.085 1.35 (1.08-1.69) 0.009
Myocardial infarction All MI 61 (0.8%) 14 (1.2%) 1.53 (0.80-2.94) 0.200 1.38 (0.71-2.68) 0.350 1.36 (0.99-1.86) 0.060
Target vessel MI 32 (0.4%) 9 (0.8%) 1.95 (0.93-4.09) 0.076 1.79 (0.81-3.97) 0.149 2.10 (1.38-3.22) <0.001
Non-target vessel MI 29 (0.4%) 5 (0.4%) 1.53 (0.52-4.53) 0.440 1.26 (0.55-2.91) 0.583 0.74 (0.45-1.23) 0.244
Revascularisation Any revascularisation 493 (6.1%) 111 (9.4%) 1.58 (1.29-1.94) <0.001 1.47 (1.18-1.83) 0.001 1.58 (1.41-1.76) <0.001
Clinically driven TLR 171 (2.1%) 52 (4.4%) 2.13 (1.56-2.91) <0.001 2.03 (1.47-2.80) <0.001 2.54 (2.14-3.01) <0.001
Clinically driven TVR 238 (3.0%) 64 (5.4%) 1.89 (1.43-2.49) <0.001 1.82 (1.36-2.42) <0.001 2.21 (1.91-2.57) <0.001
POCO 823 (10.2%) 193 (16.3%) 1.65 (1.41-1.93) <0.001 1.45 (1.23-1.71) <0.001 1.48 (1.36-1.61) <0.001
Definite or probable stent thrombosis 36 (0.4%) 12 (1.0%) 2.30 (1.19-4.41) 0.013 2.17 (1.10-4.28) 0.026 2.20 (1.51-3.20) <0.001
Adjusted for the following covariates: age, DM, hypertension, dyslipidaemia, PVD, CKD, current smoker, AMI, previous MI, previous CHF, previous CVA, left main disease, bifurcation lesion, tortuous lesion, calcification lesion, previously treated lesion, and left ventricular dysfunction (EF <40%). AMI: acute myocardial infarction; CHF: congestive heart failure; CKD: chronic kidney disease; CVA: cerebrovascular accident; DM: diabetes mellitus; EF: ejection fraction; MI: myocardial infarction; POCO: patient-oriented composite outcome; PVD: peripheral vascular disease; TLR: target lesion revascularisation; TVR: target vessel revascularisation