Table 1. Study population characteristics.
| Patients, n | Total | Type 1 | Type 2A | Type 2B | Type 3 | Type 4 | p-value |
| Patients, n | Total | Type 1 | Type 2A | Type 2B | Type 3 | Type 4 | p-value |
| 302 (100) | 52 (17.2) | 80 (26.5) | 69 (22.8) | 20 (6.6) | 81 (26.8) | ||
| Date of diagnosis* | April 2017 (March 2015, May 2018) | July 2016 (Dec. 2010, August 2017) | Dec. 2016 (Nov. 2014, Nov. 2017) | October 2017 (Feb 2015, Sept. 2018) | Dec. 2016 (Oct. 2014, June 2018) | Nov.2017 (Dec. 2015, Nov. 2018) | 0.431 |
| Female | 267 (88.4) | 42 (80.7) | 73 (91.3) | 62 (89.9) | 17 (85.0) | 73 (90.1) | 0.381 |
| Age, years | 51.8±10 | 50.6±11.2 | 50.6±8.9 | 53.6±9.7 | 50.9±9.1 | 52.6±10.7 | 0.369 |
| Cardiovascular risk factors | |||||||
| Diabetes | 8 (2.6) | 0 | 2 (2.5) | 4 (5.8) | 0 | 2 (2.5) | 0.451 |
| Dyslipidaemia | 108 (35.8) | 15 (28.8) | 28 (40.6) | 28 (40.6) | 6 (30) | 31 (38.3) | 0.613 |
| Hypertension | 104 (34.4) | 15 (28.8) | 23 (28.8) | 33 (47.8) | 7 (35) | 26 (32.1) | 0.096 |
| Current smoker | 85 (28.1) | 20 (38.5) | 19 (23.8) | 17 (24.6) | 6 (30) | 23 (28.4) | 0.629 |
| Family history of CAD | 86 (28.5) | 14 (26.9) | 20 (25) | 24 (34.8) | 3 (15) | 25 (30.8) | 0.385 |
| Other medical history | |||||||
| Hypothyroidism | 33 (10.9) | 4 (7.7) | 13 (16.3) | 7 (10.1) | 1 (5.1) | 8 (9.9) | 0.471 |
| Migraine | 57 (18.9) | 10 (19.2) | 16 (20) | 16 (23.2) | 2 (10) | 13 (16) | 0.690 |
| Anxiety | 82 (27.2) | 11 (21.2) | 22 (27.5) | 18 (26.1) | 8 (40) | 23 (28.4) | 0.418 |
| Depression | 45 (14.9) | 6 (11.5) | 12 (15.0) | 12 (17.4) | 3 (15) | 12 (14.8) | 0.885 |
| OB/GYN history | |||||||
| Post-menopausal | 96 (31.8) | 9 (17.3) | 26 (32.5) | 30 (43.5) | 5 (25) | 26 (32.1) | 0.029 |
| Hormonal therapy | 40 (13.2) | 8 (15.4) | 13 (16.3) | 6 (8.7) | 2 (10) | 11 (13.6) | 0.675 |
| Recent pregnancy | 6 (2.0) | 4 (7.7) | 2 (2.5) | 0 | 0 | 0 | 0.023 |
| Precipitating factors | |||||||
| Emotional stress | 77 (29.5) | 12 (27.2) | 21 (30.9) | 17 (30.3) | 9 (47.7) | 18 (25.2) | 0.398 |
| Physical stress | 28 (10.7) | 4 (9.2) | 12 (18.0) | 5 (8.9) | 3 (15.9) | 4 (5.6) | 0.127 |
| Data are presented as means±SDs for continuous variables or median ±interquartile range if required, and numbers (%) for categorical variables. *Dates are described with mean and interquartile range. CAD: coronary artery disease; OB/GYN: obstetrics and gynaecology | |||||||