TABLE 1.
Inclusion | Exclusion | |
Population | Patients (adults or children) with confirmed COVID-19 based on RT-PCR or clinically highly suspect cases | Studies which only referenced “COVID-19” broadly |
Exposure | Severe asthma diagnosed by clinicians or by validated or nonvalidated guidelines | Self-reported asthma patients |
Comparator | Patients (adults or children) with confirmed COVID-19 based on RT-PCR and without pre-existing severe asthma diagnosis | Studies without any comparator |
Outcome | 1) Risk of hospitalisation for people with severe asthma 2) Risk of ICU admission/mechanical ventilation for people with severe asthma 3) Risk of death for people with severe asthma |
1) Asymptomatic or mild to moderate COVID-19 symptoms 2) Studies focusing only on the pathophysiology of COVID-19 in asthma or severe asthma |
Study design | Studies of any design besides those specified in the exclusion criteria | Modelling studies, opinion pieces, editorials, reviews and laboratory studies |
Geographical location | Studies conducted in any country or countries | No restrictions based on geographical location |
COVID-19: coronavirus disease 2019; RT-PCR: reverse transcriptase PCR; ICU: intensive care unit.