|
|
| TTE variables |
Baseline |
One year |
Changea
|
p-valueb
|
Two years |
Changea
|
p-valueb
|
| Left ventricular ejection fraction, % |
57.5±10.8 (28) |
59.3±6.4 (21) |
2.5±8.3 |
0.206 |
57.7±7.0 (16) |
0.2±7.6 |
0.907 |
| Estimated systolic pulmonary artery pressure, mmHg |
35.9±10.5 (29) |
38.1±9.0 (23) |
1.4±9.9 |
0.513 |
39.5±10.9 (15) |
4.4±11.2 |
0.150 |
| PISA EROA, cm2
|
0.78±0.49 (25) |
0.37±0.18 (16) |
–0.36±0.40 |
0.004 |
0.34±0.23 (11) |
–0.57±0.47 |
0.004 |
| Mean vena contracta, cm |
1.23±0.40 (25) |
0.85±0.30 (18) |
–0.36±0.41 |
0.005 |
0.79±0.51 (10) |
–0.55±0.40 |
0.004 |
| TV annulus mid-diastolic septolateral diameter – 4CH view, mm |
43.4±5.0 (30) |
36.9±4.0 (21) |
–6.8±4.5 |
<0.001 |
34.2±4.40 (12) |
–9.8±4.2 |
<0.001 |
| TV annulus end-diastolic septolateral diameter – 4CH view, mm |
41.9±4.6 (26) |
36.5±4.6 (19) |
–5.7±3.2 |
<0.001 |
35.2±4.6 (14) |
–6.6±6.7 |
0.006 |
| RV end-diastolic diameter (mid), cm |
3.8±0.6 (29) |
3.5±0.5 (18) |
–0.1±0.5 |
0.294 |
3.2±0.6 (15) |
–0.4±0.6 |
0.014 |
| Fractional area change, % |
35.8±6.5 (29) |
35.4±5.3 (16) |
–0.4±5.7 |
0.795 |
37.9±6.9 (15) |
2.5±6.2 |
0.142 |
| RV TAPSE, cm |
1.4±0.3 (22) |
1.4±0.4 (22) |
–0.1±0.3 |
0.462 |
1.4±0.4 (16) |
0.1±0.2 |
NS |
| Right atrial volume, mL |
127±45 (30) |
116±46 (20) |
–14±36 |
0.103 |
104±49 (15) |
–18±41 |
0.112 |
| Values are mean±SD (n). aChanges (mean±SD [n]) were calculated for paired observations. bp-values were calculated by Student’s t-test for paired observations. CH: chamber; LV: left ventricle; PISA EROA: proximal isovelocity surface area effective regurgitant orifice area; RV: right ventricle; TAPSE: tricuspid annular plane systolic excursion; TR: tricuspid regurgitation; TTE: transthoracic echocardiography; TV: tricuspid valve |
