Roozbeh 2007.

Study characteristics
Methods	Study characteristics Study design: parallel RCT Study duration: not reported Study follow‐up: 8 week
Participants	Baseline characteristics Country: Iran Setting: not reported Inclusion criteria: ESKD patients Randomised number (intervention/control): 30/30 Dialysis modality: HD Age: not reported Sex: not reported Dialysis duration: not reported Exclusion criteria: not reported
Interventions	Intervention group L‐carnitine (oral): 500 mg/day for 8 weeks Control group Placebo
Outcomes	Outcomes relevant to this review Muscle symptoms: weakness
Notes	Other information Abstract‐only publication Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	The method of randomisation was not reported
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias)	Low risk	Quote: "double‐blind placebo‐controlled" study
Blinding of outcome assessment (detection bias) Muscle symptoms	Low risk	Quote: "double‐blind placebo‐controlled" study
Incomplete outcome data (attrition bias) Muscle symptoms	Low risk	No missing outcome data
Selective reporting (reporting bias)	Unclear risk	The study protocol is not available
Other bias	Unclear risk	Insufficient information to permit judgement