Table 3. Surgical left main revascularisation procedures according to region of enrolment.
CABG procedural characteristics |
European Union (n=541) |
North America (n=371) |
p-value |
Odds ratio [95% CI] |
---|---|---|---|---|
Time from randomisation to first procedure, days | 8.4±18.4 | 4.3±4.4 | <0.0001 | – |
Total SYNTAX score (core lab) | 27.4±9.9 | 24.1±9.3 | <0.0001 | – |
Bypass duration, mins | 79.8±35.7 | 87.5±52.7 | 0.45 | – |
Off-pump CABG | 200/520 (38.5%) | 56/359 (15.6%) | <0.0001 | 3.38 [2.42-4.73] |
Cross-clamp duration, mins | 54.9±27.6 | 55.3±27.5 | 0.98 | – |
Intermittent cross-clamp</p> | 72/320 (22.5%) | 109/303 (36.0%) | 0.0002 | 0.52 [0.36-0.73] |
Number of grafts per subject, total | 2.7±0.8 | 2.8±0.8 | 0.30 | – |
Arterial conduits | 1.5±0.7 | 1.2±0.5 | <0.0001 | – |
Venous conduits | 1.0±0.9 | 1.5±0.9 | <0.0001 | – |
Any internal mammary artery used per individual | 511/517 (98.8%) | 355/359 (98.9%) | 1.00 | 0.96 [0.27-3.43] |
Only arterial grafts used | 176/520 (33.8%) | 40/359 (11.1%) | <0.0001 | 4.08 [2.80-5.94] |
Number of native vessels bypassed | 2.2±0.5 | 2.3±0.6 | 0.006 | – |
Haemodynamic support used during procedure | 17/520 (3.3%) | 14/359 (3.9%) | 0.62 | 0.83 [0.41-1.71] |
Intraoperative epi-aortic ultrasound | 11/520 (2.1%) | 102/359 (28.4%) | <0.0001 | 0.05 [0.03-0.10] |
Intraoperative transoesophageal echocardiogram | 154/520 (29.6%) | 225/359 (62.7%) | <0.0001 | 0.25 [0.19-0.33] |
Procedural complications* | 46/520 (8.8%) | 39/359 (10.9%) | 0.32 | 0.80 [0.51-1.25] |
Time from anaesthesia to skin closure, mins | 232.5±66.1 | 257.8±76.7 | <0.0001 | – |
Days of in-patient hospitalisation | 14.4±10.6 | 10.0±6.9 | <0.0001 | – |
Data are n (%) or mean±SD. *Aortic dissection; supraventricular tachycardia; ventricular tachycardia/fibrillation; bradyarrhythmia; deep sternal wound infection; dialysis; hypotension; hypoxaemia; neurologic dysfunction; repeat sternotomy for bleeding; respiratory failure/prolonged intubation; renal failure; sepsis or endocarditis; stroke; injury to a cardiac structure. CABG: coronary artery bypass graft |