Table 3. Detection of intimal and medial calcification in all 438 sections.

	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	Diagnostic accuracy (95% CI)
Intima OFDI	79.2% (73.4-84.3%)	86.0% (80.5-90.4%)	86.3% (81.7-89.9%)	78.8% (74.1-82.8%)	82.4% (78.5-85.9%)
Intima IVUS	84.0% (78.6-88.5%)	85.0% (79.4-89.6%)	86.2% (81.8-89.7%)	82.6% (77.9-86.5%)	84.5% (80.7-87.7%)
Media OFDI	65.3% (59.0-71.3%)	85.0% (79.1-89.7%)	84.7% (79.6-88.7%)	65.9% (61.7-69.8%)	74.0% (69.6-78.0%)
Media IVUS	66.9% (60.7-72.8%)	80.3% (74.0-85.7%)	81.2% (76.2-85.3%)	65.7% (61.2-69.9%)	72.8% (68.4-76.9%)
CI: confidence interval; IVUS: intravascular ultrasound; NPV: negative predictive value; OFDI: optical frequency domain imaging; PPV: positive predictive value