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. 2021 Sep 20;17(7):569–575. doi: 10.4244/EIJ-D-20-00853

Table 2. Comparison of individual MACE between patients with normal versus abnormal CFR/HMR.

All patients N=610 CFR ≥2.5 N=398 CFR <2.5 N=212 p-value HMR ≤2.0 N=495 HMR >2.0 N=115 p-value
Composite MACE, n (%) 174 (29) 105 (26) 69 (33) 0.11 130 (26) 44 (38) 0.01
Death, n (%) 96 (16) 60 (15) 36 (17) 0.54 70 (14) 26 (23) 0.02
Myocardial infarction, n (%) 35 (6) 22 (6) 13 (6) 0.76 24 (5) 11 (10) 0.05
Revascularisation, n (%) 38 (6) 24 (6) 14 (7) 0.78 28 (6) 10 (9) 0.22
Stroke, n (%) 30 (5) 15 (4) 15 (7) 0.07 27 (5) 3 (3) 0.20
CFR: coronary flow reserve; HMR: hyperaemic microvascular resistance; MACE: major adverse cardiovascular events