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. 2021 Dec 17;17(12):e1024–e1032. doi: 10.4244/EIJ-D-21-00295

Table 2. Change in ambulatory and office blood pressure at 2 and 6 months.

Pre-crossover baseline* 2 months* Change from pre-crossover baseline to 2M p-value* Pre-crossover baseline# 6 months# Change from pre-crossover baseline to 6M p-value
Daytime ABP, mmHg n=33 n=33 n=27 n=27
SBP 144.1±10.1 132.8±14.5 –11.2±13.7 <0.001 144.6±11.0 133.8±16.5 –10.8±17.3 0.002
DBP 89.9±8.4 82.9±9.5 –7.1±8.9 <0.001 90.4±8.7 82.6±8.8 –7.8±11.6 <0.001
24-hour ABP, mmHg n=33 n=33 n=27 n=27
SBP 137.6±11.2 126.5±14.6 –11.1±13.3 <0.001 138.9±11.7 128.6±15.6 –10.2±16.0 <0.001
DBP 85.2±8.7 78.0±9.1 –7.3±8.6 <0.001 86.1±8.9 78.5±8.0 –7.6±10.8 <0.001
Night-time ABP, mmHg n=33 n=33 n=27 n=27
SBP 127.4±15.3 116.6±16.4 –10.9±14.1 <0.001 129.9±15.3 120.5±16.2 –9.3±15.6 0.003
DBP 77.7±10.6 70.4±10.0 –7.2±9.4 <0.001 79.2±10.3 72.1±9.0 –7.1±10.6 <0.001
Office BP, mmHg n=31 n=31 n=26 n=26
SBP 146.4±18.3 139.9±17.5 –6.5±18.0 0.025 145.6±20.9 142.1±20.0 –3.5±1 9.4 0.393
DBP 94.6±10.4 89.4±11.1 –5.3±10.3 0.003 94.7±10.4 91.6±10.7 –3.1±10.8 0.170
Data displayed as mean±SD. p-value for change from baseline is from signed-rank test. *Matched 2-month data. #Matched 6-month data. ABP: ambulatory blood pressure; BP: blood pressure; DBP: diastolic blood pressure; SBP: systolic blood pressure