Figure 8.

Application of multiple statistical methods to cardiovascular disease trials. Weight 1: death, 1.0; CVA or stroke, 0.47; MI, 0.38; TVR, 0.25. Weight 2: death, 1.0; severe stroke, 0.82; moderate stroke, 0.47; mild stroke, 0.23; severe MI, 0.59; moderate MI, 0.38; mild MI, 0.17. Weight 3: death, 1.0; shock, 0.5; CHF, 0.3; re-MI, 0.2; RI, 0.1. AG: Andersen-Gill; CABG: coronary artery bypass grafting; CI: confidence interval; CR: competing risk; CV: cardiovascular; CVA: cerebrovascular accident; GRACE: Global Registry of Acute Cardiac Events; HR: hazard ratio; LMCA: left main coronary artery disease; MI: myocardial infarction; NA: not available; NB: negative binomial; NSTEMI: non-ST-segment elevation myocardial infarction; PCI: percutaneous coronary intervention; RCT: randomised control trial; re-MI: recurrent myocardial infarction; RI: recurrent ischaemia; RR: rate ratio; STEMI: ST-segment elevation myocardial infarction; 3VD: 3-vessel disease; TTE: time to first event; TVR: target vessel revascularisation; UA: unstable angina; UFH: unfractionated heparin; WCE: weighted composite endpoint; WR: win ratio