| Baseline echo parameters |
Patient #1 |
Patient #2 |
Patient #3 |
Patient #4 |
Patient #5 |
Patient #6 |
| LAESVI, ml/s2
|
1,068.9 |
401.3 |
159.7 |
94.9 |
89.3 |
306.3 |
| LVEDVI, ml/s2
|
97.1 |
56.6 |
45.6 |
83.2 |
56.4 |
68.0 |
| LVEF, % |
60 |
60 |
64 |
56 |
70 |
55 |
| RAESVI, ml/s2
|
167.3 |
145.7 |
75.1 |
126.0 |
319.5 |
330.5 |
| RVEDAI, cm2/s2
|
14.3 |
16.5 |
13.7 |
16.1 |
24.6 |
28.9 |
| TAPSE, cm |
1.5 |
1.8 |
2.0 |
1.2 |
1.3 |
1.1 |
| RV fractional area change, % |
25 |
45 |
47 |
23 |
22 |
48 |
| RV global longitudinal strain, % |
–13.7 |
–10.2 |
–12.6 |
–15.7 |
–14.9 |
–12.8 |
| Mean transvalvular gradient, mmHg |
2.2 |
4.6 |
3.7 |
3.3 |
6.6 |
4.5 |
| TR defining parameters |
EROA, cm2
|
1.0 |
0.7 |
1.1 |
0.9 |
1.2 |
0.8 |
| VC width, mm |
11 |
8 |
13 |
10 |
16 |
9 |
| IVC, mm |
28 |
24 |
29 |
28 |
30 |
32 |
| TR grade |
Torrential |
Massive |
Torrential |
Torrential |
Torrential |
Torrential |
| TV annular diameter (4Ch, end-diastole), cm |
4.0 |
4.1 |
4.1 |
4.6 |
4.7 |
4.4 |
| Minimum/maximum diameters of TV annular (3D TEE, end-diastolic), cm |
3.8×4.1 |
4.0×4.3 |
4.1×4.2 |
4.1×4.6 |
4.1×4.7 |
4.0×4.5 |
| Baseline CT annular measurements (end-diastolic) |
Minimum/maximum diameters, cm |
3.9×4.3 |
3.9×4.4 |
4.0×4.2 |
4.2×4.8 |
4.3×5.0 |
4.1×4.7 |
| LuX-Valve model implanted |
JS/TTVI-28-50 |
JS/TTVI-28-50 |
JS/TTVI-28-50 |
JS/TTVI-28-55 |
JS/TTVI-28-55 |
JS/TTVI-28-55 |
| Release time of the guiding sheath, min |
10.7 |
6.2 |
8.5 |
9.8 |
13.6 |
9.1 |
| Intraprocedural, post-device TEE |
Tricuspid regurgitation, total |
Moderate |
No |
No |
Mild |
Mild |
Mild |
| Central |
No |
No |
No |
No |
No |
No |
| Paravalvular |
Moderate |
No |
No |
Mild |
Mild |
Mild |
| One-year follow-up, post-device TTE |
RAESVI, ml/s2
|
/ |
85.9 |
56.4 |
93.3 |
105.4 |
152.0 |
| RVEDAI, cm2/s2
|
/ |
9.7 |
8.3 |
11.5 |
19.8 |
17.7 |
| TAPSE, cm |
/ |
2.0 |
1.8 |
1.7 |
1.5 |
1.9 |
| RV fractional area change, % |
/ |
47 |
39 |
32 |
26 |
40 |
| RV global longitudinal strain, % |
/ |
–17.5 |
–19.3 |
–22.1 |
–20.4 |
–18.2 |
| Mean transvalvular gradient, mmHg |
/ |
3.1 |
2.4 |
1.8 |
4.1 |
2.2 |
| Tricuspid regurgitation, total |
/ |
No |
No |
Mild |
Mild |
Mild |
| Central |
/ |
No |
No |
No |
No |
No |
| Paravalvular |
/ |
No |
No |
Mild |
Mild |
Mild |
| CT: computed tomography; EROA: effective regurgitant orifice area; IVC: inferior vena cava; LAESVI: left atrium end-systolic volume index; LVEDVI: left ventricular end-diastolic volume index; LVEF: left ventricular ejection fraction; RAESVI: right atrium end-systolic volume index; RV: right ventricular; RVEDAI: right ventricular end-diastolic area index; TAPSE: tricuspid annular plane systolic excursion; TEE: transoesophageal echocardiography; TR: tricuspid regurgitation; TV: tricuspid valve |
